Theme Leader - Epigenetics, Wisconsin Institute for Discovery
Wisconsin Institute for Discovery, 330 N. Orchard Street
The Denu lab investigates the mechanisms and biological function of reversible protein modifications involved in modulating signal transduction, chromatin dynamics and metabolism. We are addressing three major areas: 1.) Writing, reading and editing a molecular language/code 2.) Linking metabolism with the epigenome, and 3.) Sirtuins and reversible protein acetylation.