1111 Highland Ave WIMR 4553, Madison WI 53705
The Kreeger lab utilizes systems biology and tissue engineering to analyze how cells respond to information from their surroundings in order to make decisions. We utilize an iterative approach, where we develop model culture systems that allow us to study diseases and physiological processes in a controlled environment, use a variety of high-throughput experimental methods to gather information about the cellular signaling network, and employ computational models to interpret the data. Current projects in the lab apply these methods to study ovarian cancer, angiogenesis, and wound healing. Ultimately, our models will be utilized to identify new drug targets, match patients to the most effective drugs, and identify methods to direct cellular behavior in tissue engineering.