Faculty

Our research is directed at developing and applying computational and experimental tools to understand the systems-scale evolution of complex traits like virulence and host-range of bacteria. Much of our work focuses on the family Enterobacteriaceae, which includes biomedically and agriculturally relevant pathogens, as well as mutualists, commensals and environmental organisms. Our work is providing important insights into the tempo and mode of evolution of bacterial genomes, and the metabolic and regulatory networks that impact pathogenesis.